Understanding HRT and BHRT
Hormone Replacement Therapy (HRT)
HRT involves using synthetic hormones or hormones derived from animal sources to replace the hormones that decline during menopause. These hormones are often standardized and may not exactly match the molecular structure of human hormones.
Bioidentical Hormone Replacement Therapy (BHRT)
BHRT uses hormones that are chemically identical to those produced by the human body. These hormones are typically derived from plant sources and are customized to match each individual’s unique hormonal needs.
Key Differences
Molecular Structure
HRT: Uses hormones that may have a slightly different structure than human hormones.
BHRT: Uses hormones that are molecularly identical to human hormones.
Customization
HRT: Often comes in standardized doses.
BHRT: Can be customized to each woman’s specific hormonal profile.
Absorption and Metabolism
HRT: May be metabolized differently due to its synthetic nature.
BHRT: Often metabolized more efficiently as it mimics the body’s natural hormones.
Side Effects
HRT: May have a higher risk of side effects due to its synthetic nature.
BHRT: Often associated with fewer side effects, though research is ongoing.
Functional Medicine Approach
HRT: Less aligned with functional medicine principles of personalized care.
BHRT: More closely aligns with functional medicine’s focus on individualized treatment.
Benefits and Risks
Both HRT and BHRT can offer relief from menopausal symptoms such as hot flashes, night sweats, vaginal dryness, and mood swings. They may also help protect against osteoporosis and heart disease.
However, both therapies come with potential risks, including:
- Increased risk of blood clots
- Potential increased risk of certain cancers (though research is ongoing and controversial)
- Possible side effects like bloating, breast tenderness, and nausea
The Functional Medicine Perspective
In functional medicine, we emphasize:
- Personalized care: BHRT’s customizable nature aligns well with this principle.
Root cause analysis: We look beyond symptom management to address underlying imbalances. - Holistic approach: Hormone therapy is considered alongside lifestyle factors, nutrition, and stress management.
- Minimal effective dose: We aim to use the lowest dose that effectively manages symptoms.
Making the Right Choice
The decision between HRT and BHRT should be made in consultation with a healthcare provider who understands your individual needs. Factors to consider include:
- Your specific symptoms and health goals
- Your personal and family medical history
- Your preferences and values regarding treatment approaches
Remember, hormone therapy is just one tool in managing menopausal symptoms. A comprehensive approach including diet, exercise, stress management, and targeted supplementation can support hormonal balance and overall well-being during this transitional period.
Ask Dr. Corrine about HRT and BHRT
While both HRT and BHRT can be effective in managing menopausal symptoms, BHRT often aligns more closely with functional medicine principles due to its personalized nature and bioidentical structure. However, the best choice depends on your individual circumstances. Always work with a qualified healthcare provider to determine the most appropriate approach for your unique needs. At Legacy Physicians, we are here to guide you on this journey, offering personalized care and expert advice tailored to your unique needs. Schedule a consultation with Dr. Corinne at Legacy Physicians.
Dr. Corinne Rao is a leading expert in Lifestyle Medicine and Functional Medicine, dedicated to helping patients achieve optimal health through evidence-based practices and personalized care.



